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Drug Discovery and Development: Technology in Transition, by Raymond G Hill
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The modern pharmacopeia has enormous power to alleviate disease, and owes its existence almost entirely to the work of the pharmaceutical industry. This book provides an introduction to the way the industry goes about the discovery and development of new drugs. The first part gives a brief historical account from its origins in the mediaeval apothecaries’ trade, and discusses the changing understanding of what we mean by disease, and what therapy aims to achieve, as well as summarising case histories of the discovery and development of some important drugs. The second part focuses on the science and technology involved in the discovery process: the stages by which a promising new chemical entity is identified, from the starting point of a medical need and an idea for addressing it. A chapter on biopharmaceuticals, whose discovery and development tend to follow routes somewhat different from synthetic compounds, is included here, as well as accounts of patent issues that arise in the discovery phase, and a chapter on research management in this environment. The third section of the book deals with drug development: the work that has to be undertaken to turn the drug candidate that emerges from the discovery process into a product on the market.
- Sales Rank: #807694 in eBooks
- Published on: 2012-07-20
- Released on: 2012-07-20
- Format: Kindle eBook
Most helpful customer reviews
0 of 0 people found the following review helpful.
Truly Exemplary Book!
By Nate K
Coming up with adequate superlatives to describe this book is difficult.
Suffice to say, for anyone interested in a career in pharmaceutical discovery or development, this book is an INDISPENSABLE guide, containing tons of stuff you need to know, and so far as I can tell, nothing you don't.
If not for this book, I would probably have spent countless hours scouring the internet and maybe several books to try to stitch together a similar picture. Not only would I have failed in gaining an adequate understanding of the drug industry, but I would have spent far more time failing than how long it has taken me to read this book.
It's thorough and sparing, as I mentioned before. It's clearly written. It's a brilliant mix of commercial concerns and scientific processes. I feel I am getting real "insider information" reading this book. Sure, I might not learn any secrets, but to my knowledge no one else has packaged this information in such a way as to make it accessible to anyone lucky enough to stumble upon a certain book.
So bravo, Hill, Rang et al.! You've saved me from surely burning out before even finishing my undergraduate education. You've shown me the "light at the end of the tunnel." You've helped keep me focused on what matters in my education, and given me the peace of mind to forget about anything unimportant.
*Also worth noting:
The second edition was just published last summer I believe, so the information is really up-to-date, which is obviously of utmost importance in such a rapidly progressing field.
0 of 0 people found the following review helpful.
Excellent Resource for knowledge on the Drug Discovery Process
By BstKptScrt
This is an excellent resource for anyone interested in Drug Discovery and Development as well as Clinical Research and Clinical Trials. This book discusses the process of taking a concept to development of a drug. Processes such as HTS and In Silico are discussed in this book as well as the different phases of a clinical trial. This is an excellent resource that is very informative and a pleasure to read!
0 of 0 people found the following review helpful.
Excellent Text Book
By San Mateo PJ
This textbook is an excellent insight into the thinking, strategy and tactics behind modern Drug Discovery and Development - Highly Recommended
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